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If you take mefenamic acid for a long period of timeyour doctor may want to check you on a regular basis to make sure this medication is not causing harmful effectsDo not miss any scheduled visits to your doctor.
Mefenamic acid pharmacokinetics have not been investigated in subjects with renal insufficiencyGiven that mefenamic acidits metabolites and conjugates are primarily excreted by the kidneysthe potential exists for mefenamic acid metabolites to accumulatePonstel should not be administered to patients with pre-existing renal disease or in patients with significantly impaired renal functionsee WARNINGSRenal Toxicity and Hyperkalemia
Seek emergency medical help if you have symptoms of heart or circulation problemssuch as chest painweaknessshortness of breathslurred speechor problems with vision or balance.
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